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A Phase 1, First in Human, Dose-Escalation Study of TORL-1-23 in Participants with Advanced Cancer

Status: Recruiting
This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer.
Age: 18 years and over
Healthy Volunteers:
Inclusion Criteria:
• advanced solid tumor
• restricted strenuous physical activity but can walk and able to carry light work e.g., light house work, office work
Exclusion Criteria:
• progressive or symptomatic brain metastases
• serious, uncontrolled medical disorder or active, uncontrolled infection
• history of significant hear disease
• history of another cancer within 3 years
• women who are pregnant or breast feeding
• contact study staff for additional exclusion criteria
Conditions:
Cancer
Keywords:
Clinics and Surgery Center (CSC), Advanced Solid Tumor, Endometrial Cancer, NSCLC, Ovarian Cancer
Contact(s): Boris Winterhoff - bwinterh@umn.edu
Principal Investigator: Boris Winterhoff
Phase: PHASE1
IRB Number: STUDY00014893
System ID: 36844
See this study on ClinicalTrials.gov