StudyFinder
Transdiagnostic Cognitive Biomarkers
Status: Recruiting
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.
Age: 18 years and over
Healthy Volunteers:
Inclusion Criteria:
• all participants must be adults 18 years or older
• diagnosis of chronic pain that isn't controlled with oral pain medication OR
• diagnosis of major depression OR
• healthy volunteers
Exclusion Criteria:
• unable to have TMS due to metallic hardware (such as cochlear implants, deep brain stimulator, medication pumps)
• history of seizures or epilepsy
• unable to have a MRI
• unable to complete tasks associated with study
• women who are pregnant
• non-English speaking
• blindness
• healthy volunteers may not have a diagnosis of chronic pain or depression
Conditions:
Brain & Nervous System, Mental Health & Addiction
Keywords:
Depression, chronic pain, pain, MRI, TMS
Contact(s): Gabby Hernandez - hern0245@umn.edu
Principal Investigator: David Darrow
Phase: NA
IRB Number: STUDY00011759
System ID: 32102
See this study on ClinicalTrials.gov