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Transdiagnostic Cognitive Biomarkers
Recruiting
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.
18 years and over
Inclusion Criteria:
• all participants must be adults 18 years or older
• diagnosis of chronic pain that isn't controlled with oral pain medication OR
• diagnosis of major depression OR
• healthy volunteers
Exclusion Criteria:
• unable to have TMS due to metallic hardware (such as cochlear implants, deep brain stimulator, medication pumps)
• history of seizures or epilepsy
• unable to have a MRI
• unable to complete tasks associated with study
• women who are pregnant
• non-English speaking
• blindness
• healthy volunteers may not have a diagnosis of chronic pain or depression
Behavioral: Computer game/task, Behavioral: Health surveys online
Brain & Nervous System, Mental Health & Addiction
Depression, chronic pain, pain, MRI, TMS
Gabby Hernandez - hern0245@umn.edu
David Darrow
NA
STUDY00011759
32102
See this study on ClinicalTrials.gov