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Mechanisms of Rigidity Enhancement with an Activation Maneuver in Parkinson's Disease
Recruiting
This study will investigate neural mechanisms underlying the enhancement of rigidity with an activation maneuver (contralateral voluntary movement such as hand tapping) in people with Parkinson's disease. Rigidity will be measured using a custom robotic manipulandum while neural activity will be assessed using EEG and TMS protocols.
18 years and over
Inclusion Criteria:
• Diagnosis of idiopathic PD as determined by a movement disorders neurologist
• 21 to 80 years old. Healthy participants must be 18 to 80 years old.
Exclusion Criteria:
• Diagnosis of dementia
• Significant arm tremor or very limited arm movement
• History of other neurological disorders
• Pregnancy
Brain & Nervous System
Neurology, Parkinson's Disease
Joshua De Kam - jadekam@umn.edu
Colum MacKinnon
STUDY00004525
23314